I’ve used UbuntuDDE and Manjaro, and they both ran fine, although that was back on my Intel mainboard. Now, on my AMD mainboard, I currently use ZorinOS and my roommate uses Kubuntu on his. I didn’t need to switch, I just wanted to check out Zorin again. You used to have to run a script to install an OEM kernel but I think as of some recent updates that’s no longer necessary. My only negative is the battery drains a lot in sleep mode, so it’s better to shut down.
So you can set up other distributions to run Windows apps as well, Zorin just makes it a little easier. When you first try to run a Windows executable you’ll be prompted to install the necessary components to run Windows apps. After everything is set up, a decent number of windows apps can be run straight from the file browser without having to open up bottles or something. Not everything will run though, and for games you may get better performance running through bottles or lutris.