A team of researchers in Kansai is set to begin clinical trials next month to develop medicine to help grow teeth.
The researchers, including from Kitano Hospital and Kyoto University Hospital, will conduct trials for teething medicine, aimed at treating people with congenital anodontia who are born with few teeth.
To check its safety, the experimental drug will first be administered to adult men who have lost back teeth, before it is tested on children with congenital anodontia. The team aims to put the treatment into practical use in around 2030.
The article says that they hope to regrow teeth for people who have lost their teeth to cavities, and the initial test is being done on adults who have lost back teeth. So pretty much the exact target audience you say it wouldn’t target.
It’s really weird though. Why specify that you’re targeting specifically kids with a disorder when your treatment is being tested on adults, and would work on any adult who has lost teeth for any reason?
Speculating, but probably because kids without any teeth and a genetic basis of that disease would pay for this treatment out of medical coverage, not dental coverage, at least in the US, and getting it approved for specifically that indication is easier, faster, and likely higher profit than the admittedly larger population but smaller insured availability of funds that would be the dental market.
Markets shouldn’t drive drug research, public health benefit should, but shrugs
Good thought, but it looks like they’re a Japanese team conducting trials in Japan, so the US excuse for an insurance system shouldn’t be a factor? IDK
Quick search tells me that they have a national dental plan that covers 70%, but has limits on which procedures materials etc are covered. In other words, they may not cover this procedure if it’s more expensive than a traditional implant.
Additionally, there’s harmonization efforts between Japan and the US FDA; if fully expect they’re running clinical trials in JP with hopes for a later release abroad, and the US is a huge market so they’d still be angling that I’d think.
Because /hobthrob is incorrect. This medication will not and cannot be used to regrow teeth in people that don’t have the genetic disorder “congenital anodontia”. The drug can only help that >1% with the disorder.
My bad. I guess this is a completely different thing from one I read about around 6 months ago, then.
Given the average quality of science reporting and the lack of actual journal articles, it might be the same thing with a misunderstanding in either the earlier article or this one.
Oh man. It seems the only misunderstanding is that no one else in here understands the article or what congenital anodontia actually is. So what I had initially stated, and per this article, it won’t help 99% of people.
How do we not understand the article? If the article is full of bull, that’s another story
science reporting is awesome, I love when people start pushing random BS because they decided they needed to “dumb it down” because they themselves were too dumb to get it in the first place