A team of researchers in Kansai is set to begin clinical trials next month to develop medicine to help grow teeth.

The researchers, including from Kitano Hospital and Kyoto University Hospital, will conduct trials for teething medicine, aimed at treating people with congenital anodontia who are born with few teeth.

To check its safety, the experimental drug will first be administered to adult men who have lost back teeth, before it is tested on children with congenital anodontia. The team aims to put the treatment into practical use in around 2030.

  • watersnipje@lemmy.blahaj.zone
    link
    fedilink
    English
    arrow-up
    0
    ·
    25 days ago

    All I can imagine is someone in a lab tripping while carrying a tray of the stuff, spilling the tooth generation potion all over themselves.

    • ColeSloth@discuss.tchncs.de
      link
      fedilink
      English
      arrow-up
      0
      ·
      25 days ago

      Not actually. This doesn’t do anything for most normal people. It’s for people who didn’t properly have a normal 2nd set of teeth. So if you just had your “adult” set of teeth go bad, this won’t help you.

      • Hobthrob@lemmy.world
        link
        fedilink
        English
        arrow-up
        0
        ·
        25 days ago

        The article says that they hope to regrow teeth for people who have lost their teeth to cavities, and the initial test is being done on adults who have lost back teeth. So pretty much the exact target audience you say it wouldn’t target.

        • AwesomeLowlander@sh.itjust.works
          link
          fedilink
          English
          arrow-up
          0
          ·
          25 days ago

          It’s really weird though. Why specify that you’re targeting specifically kids with a disorder when your treatment is being tested on adults, and would work on any adult who has lost teeth for any reason?

          • AliasAKA@lemmy.world
            link
            fedilink
            English
            arrow-up
            0
            ·
            25 days ago

            Speculating, but probably because kids without any teeth and a genetic basis of that disease would pay for this treatment out of medical coverage, not dental coverage, at least in the US, and getting it approved for specifically that indication is easier, faster, and likely higher profit than the admittedly larger population but smaller insured availability of funds that would be the dental market.

            Markets shouldn’t drive drug research, public health benefit should, but shrugs

            • AwesomeLowlander@sh.itjust.works
              link
              fedilink
              English
              arrow-up
              0
              ·
              25 days ago

              Good thought, but it looks like they’re a Japanese team conducting trials in Japan, so the US excuse for an insurance system shouldn’t be a factor? IDK

              • AliasAKA@lemmy.world
                link
                fedilink
                English
                arrow-up
                0
                ·
                25 days ago

                Quick search tells me that they have a national dental plan that covers 70%, but has limits on which procedures materials etc are covered. In other words, they may not cover this procedure if it’s more expensive than a traditional implant.

                Additionally, there’s harmonization efforts between Japan and the US FDA; if fully expect they’re running clinical trials in JP with hopes for a later release abroad, and the US is a huge market so they’d still be angling that I’d think.

          • ColeSloth@discuss.tchncs.de
            link
            fedilink
            English
            arrow-up
            0
            ·
            24 days ago

            Because /hobthrob is incorrect. This medication will not and cannot be used to regrow teeth in people that don’t have the genetic disorder “congenital anodontia”. The drug can only help that >1% with the disorder.

          • AwesomeLowlander@sh.itjust.works
            link
            fedilink
            English
            arrow-up
            0
            ·
            25 days ago

            Given the average quality of science reporting and the lack of actual journal articles, it might be the same thing with a misunderstanding in either the earlier article or this one.

            • orrk@lemmy.world
              link
              fedilink
              English
              arrow-up
              0
              ·
              25 days ago

              science reporting is awesome, I love when people start pushing random BS because they decided they needed to “dumb it down” because they themselves were too dumb to get it in the first place

            • ColeSloth@discuss.tchncs.de
              link
              fedilink
              English
              arrow-up
              0
              ·
              24 days ago

              Oh man. It seems the only misunderstanding is that no one else in here understands the article or what congenital anodontia actually is. So what I had initially stated, and per this article, it won’t help 99% of people.

              • AwesomeLowlander@sh.itjust.works
                link
                fedilink
                English
                arrow-up
                0
                ·
                24 days ago

                The treatment may be applied in the future to people who have permanently lost teeth due to cavities and other problems.

                How do we not understand the article? If the article is full of bull, that’s another story

  • There are two possibilities, and both are pretty fucking gnarly.

    1. They grow teeth normally, giving millions of people the ability to eat solid foods again.

    2. Teeth begin growing like cancer all over your body giving you an impenetrable shell of armor.