There’s a Dracula “sci-fi western” in development now, and it wouldn’t be the first sci-fi film to feature vampires. Blade Trinity was fairly sci-fi and featured a resurrected Vlad III. There are also a whole bunch of low-budget independent films, because the character is public domain.

So it’s been done, but I wouldn’t say it’s been done well. Technology and the ubiquity of cameras make telling vampire stories logistically complicated. Like, they always need to come up with a bunch of handwaves to explain how coffins fly on airplanes piloted by a bunch of human familiars, and how the old legends about running water and being invited in are apocryphal superstitions.